Mastering Diablo 4: Complete Your Escalating Nightmares Journey

Mastering Diablo 4: Complete Your Escalating Nightmares Journey

Updated: August 01,2025 | Game: DIABLO 4
Mastering Diablo 4: Complete Your Escalating Nightmares Journey

Completing the Infusion Affix Cancelling Challenge

Many players have found that some quests in Diablo 4 Season 9 can be especially challenging, with unclear instructions. In particular, the goal of cancelling enemy affixes through the use of infusions has been a common hurdle. Here’s a simplified guide on how to efficiently tackle this task:

  • First, ensure you have equipped a seasonal Horadric Infusion from the inventory's seasonal tab.
  • To maximize your chances, dive into areas with a high density of elite enemies, such as Nightmare Dungeons or The Pit.
  • Focus on elite enemies that possess specific affixes (e.g., Vampiric, Volcanic). Engage these foes with your infusion activated.
  • Note that the infusion will need to be upgraded to at least Rank 5 to successfully trigger the cancelation of the affix.
  • After dealing with one enemy, switch to another infusion for continued progress.
  • Progress can be somewhat random, so keep track between dungeon runs.

Opening Grand Horadric Caches

The quest named Night Terrors also poses its own set of challenges. To complete it, players need to open Grand Horadric Caches in Strongrooms while participating in Escalating Nightmares.

Follow these steps to streamline your efforts:

  • Begin with activating Escalating Nightmare Dungeons. These require Legendary-quality (orange) Nightmare Sigils, which you can find in Horadric Strongrooms located within regular Nightmare Dungeons.
  • Utilize the sigil from your Consumables tab to commence an Escalating run.
  • Search for a Strongroom during your run.
  • Once you reach the conclusion of the Strongroom, you will receive a Grand Horadric Cache as a reward. Opening this will count towards the quest requiring you to open Grand Horadric Caches found in Horadric Strongrooms.
  • The second part of this quest involves completing random events inside the Escalating Dungeons (e.g., rescuing villagers, activating pillars). These events are fully RNG-based, so be prepared for a few runs before achieving this part; you will need to complete 5 events.
  • If you deplete your Escalating Sigils, consider teaming up with others. You can join their dungeons even without having your own sigils.
  • To expedite your runs, tackle these dungeons at lower Torment Tiers. You don’t necessarily need to run them in T4 unless achievement completion is your sole goal.

Armed with these community-driven tips, you should breeze through your seasonal objectives this time!

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